Difference Between Aciphex and Nexium (With Table)

Stomach cell irritation occur, characterized by reddened spots visible beneath the associate medical instrument. Throughout this point, the protecting layers weaken, which may lead to viscus acid slowly corroding the realm. Doctors prescribe medications that stop viscous contents from turning too acidic. These medications square measure Nexium and Aciphex, and they have their variations.

Aciphex  vs  Nexium

The main difference between Aciphex and Nexium is that they’re the generic names for various medications. Aciphex is the generic name used for the drug referred to as Rabeprazole whereas Esomeprazole is the primary drug named Nexium has been chosen because of the generic name.

Difference Between Aciphex and

The first medication is Nexium, which is the name of Esomeprazole. It’s been used a few times currently, and it’s been proved to be effective in reducing discomfort from viscus acid increase within the abdomen. Nexium could be a proton-pump substance that prevents the formation of digestive juice by inhibiting enzymes that square measure chargeable for digestive juice production. Nexium relieves heartburns or abdomen upsets, similarly as preventing these from continuing.

On the opposite hand, there’s Aciphex, which is the name for Rabeprazole. It’s another proton-pump inhibitor style that is tested for short-run relief from complaints of viscus upsets caused by acidity. Aciphex incorporates a quicker impact than Nexium, and patients will feel relief a touch faster. Aciphex is additionally a replacement generation of proton-pump inhibitors created to forestall ulcerations similarly.

Comparison Table Aciphex and Nexium

Parameters of ComparisonAciphex               Nexium
FDAFor the primary time, Aciphex was approved by a government agency on nineteenth August 1999.               On the twenty-third Gregorian calendar month 2015, Nexium was supported by a government agency
Brand/Generic NameAciphex is the disapproval name for the drug RabeprazoleNexium is the generic term used for a drug named Esomeprazole
Dosage TypeAciphex solely comes within the pill version.Nexium is out there in 3 completely different versions that embody pills, injections, and packets.  
Side EffectsAciphex may also result in severe facet effects like an infectious disease, swelling, muscle pain, joint pain, etc.A couple of facet effects will be caused by Nexium square measure diarrhoea, vomiting, headaches, abdomen ache, gas, etc.
EffectivenessAciphex shows its effectiveness quickerNexium works a bit late than Aciphex.  

What is Aciphex?

Aciphex (rabeprazole sodium) could be a nucleon pump substance (PPI) to cut back abdomen acid and is employed for the treatment of reflux disorder (GERD), small intestine ulcers, and used in combination with antibiotics to treat Helicobacter pylori (H. pylori) microorganism infections within the abdomen. Aciphex is out there as generic termed rabeprazole metal. Aciphex is out there in twenty mg strength enteric-coated tablets. The same old dose of Aciphex is one twenty mg pill per day for four to eight weeks.

Aciphex might move with atazanavir, blood thinners, digoxin, diuretics (water pills), ketoconazole, amethopterin, or cyclosporine. Tell your doctor all medications and supplements you utilize.

What is Nexium?

Nexium (esomeprazole magnesium) could be a nucleon pump substance that decreases the quantity of acid created within the abdomen.

Nexium is employed to treat reflux disorder symptoms (GERD) and alternative conditions involving excessive abdomen acid-like Zollinger-Ellison syndrome. It’s conjointly accustomed to promoting healing of erosive redness (damage to your muscular structure caused by abdomen acid).

Nexium may tend to forestall peptic ulceration caused by infection with Helicobacter pylori (H. pylori) or by utilizing anti-inflammatory medication (NSAIDs).

Nexium isn’t for immediate relief of pyrosis symptoms.

Main Difference Between  Aciphex and Nexium

  1. Nexium is the name for Esomeprazole, which could be a proton-pump substance that gives relief from viscus upsets and accrued acid production.
  2. Aciphex is the name for Rabeprazole, a replacement generation of proton-pump inhibitors. It’s similar effects to Esomeprazole and is prescribed for viscus upsets and forestall ulcerations.
  3. Aciphex has been proved to figure quicker than Nexium for short-run relief of abdomen discomfort.
  4. Hepatitis, swelling, muscle pain, joint pain, etc., square measure some facet effects of Aciphex. On the opposite hand, Nexium will affect our body negatively wherever its facet effects embody diarrhoea vomiting, headaches, abdomen ache, gas, etc.
  5. It takes less time for Aciphex to indicate its effects upon the patient’s body, whereas on the opposite hand, Nexium relatively takes an extended time to figure.


As we’ve returned to grasp, Aciphex and Nexium square measure two medications used for curring abdomen conditions. Folks ignore abdomen issues; however, later, it’d cause severe problems like abdomen ulcers, so the doctors visit various medications and Aciphex and Nexium square measure a number of them. Most medication used for each of them square measure completely different from one another. The effectiveness conjointly differs from one another. Their strengths conjointly take issue from one another, and the doctors visit the patients in step with their kind.


  1. https://europepmc.org/article/med/12120118
  2. https://pubmed.ncbi.nlm.nih.gov/11111605/